Omega-3 Does Not Prevent Atrial Fibrillation

Omega-3 Does Not Prevent Atrial Fibrillation.
Omega-3 fatty acid supplements don't omission back on recurrences of atrial fibrillation, a archetype of craggy heartbeat that can cause stroke, unknown scrutinize suggests. "We now have exact data that they don't work for most patients with AF atrial fibrillation ," said Dr Peter R Kowey, leading maker of a muse about appearing in the Dec 1, 2010 go forth of the Journal of the American Medical Association that is also scheduled to be presented Monday at the American Heart Association's annual meet in Chicago. "Although we can't preclude the chance of efficacy in sicker AF patients, it would be dynamically to believe that it would form in that population and not in healthier patients yourvimax. So for personal purposes, yes, this is the end of the line in AF".

This study, the largest of its kind, looked at patients with AF who were otherwise healthy. "We cannot aver there is any convincing testimony of a place for omega-3 in the prevention of atrial fibrillation," added Dr Ranjit Suri, headman of the Electrophysiology Service and Cardiac Arrhythmia Center at Lenox Hill Hospital in New York City, who was not twisted with the trial weight loss. The look at was funded by GlaxoSmithKline.

Omega-3 fatty acids, which are found in fatty fish such as salmon and albacore tuna, had showed some contract in preventing marrow ailment in earlier trials maxelder argan cream. Of the unqualified 663 outpatient participants, 542 had paroxysmal atrial fibrillation, which appears feverishly and resolves on its own, and 121 had continuous atrial fibrillation, which needs treatment.

Participants were randomized to pick up either a placebo or 8 grams of omega-3 supplements common for the oldest week, followed by 4 grams a light of day for the residual 23 weeks of the trial. The doses reach-me-down in the cram are available only by prescription and are "higher than doses thitherto published in studies," said Dr Robert Block, a cardiologist and aide-de-camp professor of community and prevention medicine at the University of Rochester Medical Center.

At the end of six months, 46 percent of those in the placebo classify and 52 percent of those taking omega-3 supplements expert recurrences. The numbers of paroxysmal AF patients in the placebo and remedying groups who had AF recurrences were about square (48 percent and 52 percent, respectively), the investigators found.

In patients with unswerving AF, more patients in the omega-3 arm had recurrences than in the placebo company (50 percent and 33 percent, respectively). But experts haven't ruled out a plausible duty for omega-3 in other types of patients, such as those with insensitivity failure. "Our details do not address to other cardiac indications," said Kowey, who is president of the Main Line Health Heart Center and a professor of drug and clinical pharmacology at Jefferson Medical College in Philadelphia.

So "There has been conflicting facts there as well and a crystalline emergency for final studies have a fondness ours in those indications. Omega-3 may be productive in patients with intoxication triglycerides and bad overall cholesterol profiles or commoners prone to electric storms in the humanity who are at risk of sudden death". Block recommends that patients with cardiovascular infirmity eat two servings of sebaceous fish weekly, or three over-the-counter omega-3 capsules a day whos phil. In those with no cardiovascular disease, "there is no mundane exhaustive benefit," but they still might also want to have a bite fish regularly.