Treatment Of Diabetes Is Different For Men And Women

Treatment Of Diabetes Is Different For Men And Women.
Widely employed diabetes drugs have unlike gear on men's and women's hearts, a supplementary burn the midnight oil suggests. Researchers examined how three commonly prescribed treatments for exemplar 2 diabetes insincere 78 patients who were divided into three groups. One band took metformin alone, the in the second place group took metformin additional rosiglitazone (sold under the make name Avandia) and the third group took metformin and Lovaza, a type of fish oil neosize plus. Metformin reduces blood sugar oeuvre by the liver and improves insulin sensitivity.

Rosiglitazone also improves insulin touchiness and moves available fatty acids out of the blood. Lovaza lowers blood levels of another pattern of adipose called triglycerides. The researchers found that the drugs had very sundry and now and again opposite effects on the hearts of men and women, even as the drugs controlled blood sugar equally well in both genders medicine. The go into appears in the December question of the American Journal of Physiology - Heart and Circulatory Physiology.

Although metformin had promising mettle chattels in women, it caused the focus metabolism of men to burn less sugar and more fats. Chronic parching of fat by the humanity results in harmful changes that can lead to marrow failure, said the researchers, from the Washington University School of Medicine in St Louis herbalm.top. "Instead of making magnanimity metabolism more reasonable in men, metformin unparalleled made it worse, looking even more dig a diabetic heart," study older author Dr Robert Gropler said in a university information release.

And "But in women, metformin had the desired purport - lowering pot-bellied metabolism and increasing glucose perceptiveness by the heart". Taking either rosiglitazone or Lovaza with metformin seemed to modify some of the negative heart paraphernalia of metformin alone in men. Taking rosiglitazone in totting up to metformin further improved women's courage metabolism, compared to taking metformin alone.

The reckoning of Lovaza to metformin did not have a strong effect either practice for men or women, the researchers said. "Our examination suggests that we need to better define which therapies are optimal for women with diabetes and which ones are optimal for men," said Gropler, a professor of radiology. The lucubrate did not, however, test a cause-and-effect constituent between the opiate combinations and generosity changes venden el caliplus en mexico df. It showed only an association.